glutathione and neurodegenerative disease Potentiation of loss nerve cell death by the transition metals iron and copper: Implications for age-related diseases Role of oxidative stress in

10.1038/sj.gene.6364243 42 CaoL.-J.HouZ.-Y.LiH.-D.ZhangB.-K.FangP.-F.XiangD.-X.et al (2017)

Selenium-enriched foods and their ingredients: As intervention for the vicious cycle between autophagy and overloaded stress responses in Alzheimer's disease

Using the framework of iron as a catalyst for lipid peroxidation, along with evidence of lipid peroxidation and decreased glutathione (the substrate for the ferroptosis checkpoint inhibitor, glutathione peroxidase 4, GPX4), ferroptosis has been implicated as a pathological contributor promoting neuronal loss [31,32]

Nitric Oxide System Interaction: The peptide interacts with the nitric oxide system, which regulates blood vessel dilation and blood flow