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In brief, raw sequencing reads were assessed for quality using FastQC ( and adapter sequences were trimmed using Trimmomatic [44]

Thus, the loss of intracellular GSH in the presence of active generation of hydroperoxy-phospholipids could occur through several active mechanisms, including formation of GSH, export of GSSG, inadequate replenishment of GSH, or insufficient levels of GSSG reductase, each directly or indirectly dependent on the generation of hydroperoxy-phospholipids