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This review systematically unravels the intricate interplay between copper metabolism and cuproptosis, a unique copper-dependent RCD pathway, in the onset and progression of cardiovascular diseases

In pancreatic cancer cells, oncogenic K-Ras maintains the nucleotide pool via the MAPK-dependent signaling pathway, leading to MYC upregulation, and the use of MEK inhibitors reduces the incorporation of glutamine-derived nitrogen into purine nucleotides 38

Glutathione is a powerful antioxidant that helps protect cells from oxidative stress, detoxify harmful substances, and support immune function

Eur J Med Chem 158:853862