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Beyond direct radical trapping, elevated BH4 levels can also promote the synthesis of CoQ 10 (104), further enhancing ferroptosis resistance

Feske S, Skolnik EY, Prakriya M

Bull AW, Steffensen KR, Leers J et al

Table-2: Risk factors for toxicity of Paracetamol Mechanism of toxicity Acetaminophen has been postulated to cause liver injury by mechanisms including glutathione depletion, oxidative stress and mitochondrial dysfunction leading to loss of ATP