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Clinical judgment and research rigor will be critical in translating these molecular insights into standardized care

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However, in diabetic wounds, the transition from M1 to M2 is disrupted, leading to the accumulation of M1 macrophages, which produce ROS and sustain long-term inflammation

It has been found to exert a wide array of beneficial effects, including anti-inflammatory properties and the ability to promote angiogenesis (the formation of new blood vessels), which is crucial for tissue repair and regeneration