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Choline to N-acetylaspartate ratio (Cho/NAA) is regarded as one of the most important indexes of malignancy

[123] In accordance, occupancy of both the SERT and the NET has been shown with clomipramine administration in positron emission tomography studies with humans and non-human primates

This is in line with typical cholera toxin-induced secretory diarrhea in humans, while heat-labile enterotoxin only showed an increase in short-circuit-current in Caco-2 cells