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Butyrate, a short chain fatty acid abundant in the gut after the bacterial fermentation of carbohydrates, also induces tight junction assembly of ZO-1 and occludin through an AMPK-dependent pathway 82

In one such clinical trial held in 2010, 60 medical students were treated with 500 mg Glutathione capsules, & consistent and statistically significant reduction in melanin index was noted after 4 weeks

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Although unlikely to be able to remodel deep scars ( post operative scars, or those formed following significant trauma) it is reasonable to expect some reduction in scar tissue and the emergence of a more normal skin profile to take place