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If oxidative stress is sufficient and antioxidants are not, mitochondria are shut down to avoid cell lysis and ATP is down regulated, limiting synthesis of aldosterone and cortisol (Atanassova & Koeva, 2012)

10.1126/sciadv.adr8243 200 HuangH.XuH.LuoQ.HeJ.LiM.ChenH.et al

Serving as an essential cofactor for numerous enzymatic reactions, it plays a pivotal role in maintaining cellular functions and physiological homeostasis