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PMID: 12486409 Carlo MD Jr, Loeser RF

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In the introduction to the study the researchers listed the potential complications: Central steroid response (this is a nervous system adverse response), including sleeplessness, flushing, and non-positional headache, insomnia, hiccups, flushing, and increased radicular pain , represents some of the most common immediate or delayed adverse event related to epidural steroid injections. The systemic effects of corticosteroids (this is the whole body adverse response) themselves likely represent the most commonly encountered complications that result from Epidural Steroid Injection